(Saito) FC Harrison (1928)
Macroscopic morphology
Colonies on Sabouraud dextrose agar at 25°C are pink, smooth and glossy but not mucoid.
Microscopic morphology
On cornmeal following 72 hours incubation at 25°C, only globose yeast cells are produced (2.3-6.5 µm in diameter) [1270].
Special notes
This isolate is urease positive, nitrate negative, fails to grow on media containing cycloheximide, and demonstrates variable growth at 30°C. Reports of disease in the literature include hip joint sepsis [501], endophthalmitis [1801], and catheter related sepsis in an HIV positive patient [857]. FTL isolates include recovery from blood and lymph node.
FTL* in vitro susceptibility data
| AMB | KETO | FLU | ITRA | VORI | POSA |
|---|---|---|---|---|---|
| 0.25 µg/ml=2 | 0.5 µg/ml=2 | 32 µg/ml=1 | 0.25 µg/ml=2 | 0.25 µg/ml=1 | 0.06 µg/ml=1 |
| >64 µg/ml=2 | 1.0 µg/ml=1 | 4.0 µg/ml=1 | |||
| 2.0 µg/ml=1 | >8.0 µg/ml=1 |
| Drug/N | AMB/2 | FLU/3 | ITRA/4 | VORI/3 | POSA/1 | KETO/2 |
|---|---|---|---|---|---|---|
| MIC Range | 0.25 | 32->64 | 0.25-2.0 | 0.25->8.0 | 0.06 | 0.5 |
* Fungus Testing Laboratory unpublished data (CLSI M27-A2)