(Vuillemin) Tiraboschi, 1926
Macroscopic morphology
Colonies on potato dextrose agar at 25°C are variously colored (versicolored) and may range from very pale green, to greenish-beige, pinkish-green, salmon green, or dark green. Reverse is reddish to uncolored. Exudate, when present, is pink to reddish-brown. The growth rate is slow to moderate.
Microscopic morphology
Hyphae are septate and hyaline. Conidial heads are biseriate and loosely radiate. Conidiophores measure 120-700 µm in length, are hyaline to pale brown, smooth-walled and brittle (can see where many have “snapped off”). Vesicles are small (approximately 9-16 µm in diameter) and variably shaped, with metulae and phialides covering most of the vesicle. Reduced conidial structures resembling those seen in Penicillium species are common. Conidia measure 2.5-3 µm in diameter, are globose, and may be fine to distinctly roughened. Globose Hülle cells may also be present. Restricted growth at 35°C [531, 1215, 1875, 2202].
Special notes
Aspergillus versicolor has been reported as an agent of cutaneous disease, [800], onychomycosis[2247], otomycosis [521, 1972], osteomyelitis[1359], pulmonary disease[1051], and a mycetoma-like granuloma in a horse[1177]. Its mycotoxin, sterigmatocystin, has been studied in foodstuffs[1738, 1892] and in damp indoor environments[669].
FTL* in vitro susceptibility data
| AMB | CAS | ITRA | VORI | TERB | 5FC |
|---|---|---|---|---|---|
| 0.5 µg/ml=1 | 0.03 µg/ml=1 | 0.125 µg/ml=1 | 0.25 µg/ml=2 | 0.03 µg/ml=1 | 16 µg/ml=1 |
| 1.0 µg/ml=1 | 0.06 µg/ml=2 | 0.25 µg/ml=1 | 0.5 µg/ml=3 | >64 µg/ml=9 | |
| 2.0 µg/ml=5 | 0.25 µg/ml=1 | 0.5 µg/ml=3 | 1.0 µg/ml=2 | ||
| 4.0 µg/ml=1 | 4.0 µg/ml=1 | 1.0 µg/ml=2 | 2.0 µg/ml=2 | ||
| 8.0 µg/ml=1 | 32 µg/ml=1 | 4.0 µg/ml=1 | |||
| >64 µg/ml=1 |
| Drug/N | AMB/9 | CAS/7 | ITRA/8 | VORI/9 |
|---|---|---|---|---|
| MIC Range | 0.5-8.0 | 0.03>64 | 0.125-1.0 | 0.25-2.0 |
| MIC50 | 2.0 | 0.25 | 0.5 | 0.5 |
* Fungus Testing Laboratory unpublished data (NCCLS M38-A)