Wollenweber & Reinking (1925)
Macroscopic morphology
Macroscopic morphology may vary significantly on different media, and descriptions here are based upon growth on potato flakes agar at 25°C with on/off fluorescent light cycles of approximately 12 hours each. Rapid growth. Colonies woolly, frequently growing in “blooms”, initially white, becoming pink to red to brown centrally with the production of abundant chlamydoconidia. Reverse tan to brown to carmine red [2202], [1630].
Microscopic morphology
Hyphae are septate and hyaline. Conidiophores are simple or branched monophialides and polyphialides (phialides with more than one opening not delimited by a septum). Microconidia are abundant, spindle-shaped, 0-3 septate (never globose), measuring 6-26 x 2-4 µm. Macroconidia are rare, 3-5 septate, sickle-shaped, measuring 30-38 x 3-4.5 µm. The species epithet is derived from the profuse formation of brown, rough, thick-walled chlamydoconidia that occur in pairs, chains, or clumps at maturity [2202], [1630].
Special notes
Fusarium chlamydosporum, although uncommonly seen in clinical laboratories, has been reported as an etiologic agent in catheter-associated fungemia in a patient with lymphocytic lymphoma [1190] and as the etiologic agent in an invasive infection in a patient with aplastic anemia [2072]. The veterinary literature cites concurrent F. chlamydosporum and Microsphaeropsis arundinis infections in a cat [1217]. It is distinguished from more common fusaria by its red color, rough, brown chlamydoconidia, and clusters of microconidia borne from polyphialides with several openings.
FTL* in vitro susceptibility data
| AMB | ITRA | VORI |
|---|---|---|
| 0.25 µg/ml=2 | 0.25 µg/ml=2 | 1.0 µg/ml=2 |
| 0.5 µg/ml=1 | 8.0 µg/ml=1 | 8.0 µg/ml=1 |
| 1.0 µg/ml=1 | >8.0 µg/ml=1 |
| Drug/N | AMB/4 | ITRA/4 | VORI/3 |
|---|---|---|---|
| MIC Range | 0.25-1.0 | 0.25->8.0 | 1.0-8.0 |
* Fungus Testing Laboratory unpublished data (NCCLS M38-A)